منابع مشابه
leucocyte-endothelial cell adhesion in intestinal inflammation
Background-An important action of interleukin 8 (IL8) is stimulation ofgranulocytes. The object of this study was to assess the contribution ofIL8 to the leucocyte-endothelial celi interactions associated with intestinal inflammation in the rat. Methods-Two indomethacin injections (48 and 24 hours prior to the experiments) induced a longlasting ileitis in rats. The number of adherent and emigra...
متن کاملEndothelial Cell- Astrocyte Interactions
Recent advances in cell biology open the way for studying aspects of blood-brain bamer (BBB) formation and function that have puzzled investigators since Ehrlich and Goldmann first described the barrier. Although the endothelial cells in the microvessels of all tissues appear to arise from common mesodermal precursors, considerable organ-to-organ variability exists in their ultrastructure and p...
متن کاملLeucocyte-endothelial cell adhesion in a model of intestinal inflammation.
Leucocyte-endothelial cell adhesion is modulated by a variety of adhesion glycoprotein expressed on the surface of leucocytes and endothelial cells. Although in vitro studies show that these adhesion molecules mediate the decrease in leucocyte rolling velocity and the increase in leucocyte adherence and emigration associated with inflammation, there are few in vivo data to support this hypothes...
متن کاملRho GTPases and leucocyte-induced endothelial remodelling.
Leucocytes in the bloodstream respond rapidly to inflammatory signals by crossing the blood vessel wall and entering the tissues. This process involves adhesion to, and subsequent transmigration across, the endothelium, mediated by a cascade of interactions between adhesion molecules and stimulation of intracellular signalling pathways in both leucocytes and endothelial cells. This leads to cha...
متن کاملINTERVENTIONAL CARDIOLOGY AND SURGERY Simvastatin attenuates leucocyte–endothelial interactions after coronary revascularisation with cardiopulmonary bypass
Objective: To investigate the effects of preoperative simvastatin treatment on leucocyte–endothelial interactions following coronary artery bypass surgery with cardiopulmonary bypass. Design: Double blind crossover study. Experiments on polymorphonuclear cells (neutrophils) were done at the end of cardiopulmonary bypass and one hour postoperatively. Endothelial P-selectin expression and neutrop...
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ژورنال
عنوان ژورنال: Alimentary Pharmacology & Therapeutics
سال: 2007
ISSN: 0269-2813,1365-2036
DOI: 10.1111/j.1365-2036.1991.tb00535.x